Sach succeeds Charles Frank, who has been serving as CME's interim Chief Financial Officer since July 2009.
"David is a great addition to our senior management team," said Adrian Sarbu, President and CEO of CME. "His experience in technology and media companies and strategic financial management make him an excellent fit for us."
Sach previously served as CFO at Clearwire Corporation and at Millicom International Cellular, bringing a background in high-speed internet and telephony. He also held senior finance roles at France Telecom, EMI Group PLC and Thomson Professional Publishing.